EUROPAIN - EUROpean-Pain-Audit-In-Neonates

There were wide variations in treatment practices between different NICUs and different countries. Widespread use of O-SH-GA (opioids, sedatives-hypnotics, general anesthetics) in intubated neonates prolonged their need for mechanical ventilation. The availability of these data will enable comparison of practices with state-of-the-art knowledge and develop a new European standard care for pain relief in its most vulnerable population.

The most important published papers:

Carbajal R, Eriksson M, Courtous E, Boyle E, Avila-Alvarez A, Dovland Andersen R, Sarafidis K, Pölkki T, Matos C, Lago P, Papadouri T, Attard Montalto S, Ilmoja M-L, Simons S, Tameliene R, van Overmeire B, Berger A, Dobrzanska A, Schroth M, Bergqvist L, Lagercrantz H, Anand KJ; EUROPAIN Survey Working Group. Sedation and analgesia practices in neonatal intensive care units (EUROPAIN): results from a prospective cohort study. Lancet Respir Med 2015: 3(10):796-812. doi: 10.1016/S2213-2600(15)00331-8. https://pubmed.ncbi.nlm.nih.gov/26420017/

Anand KJS, Eriksson M, Boyle EM, Avila-Alvarez A, Andersen RD, Sarafidis K, Pölkki T, Matos C, Lago P, Papadouri T, Attard Montalto S, Ilmoja M-L, Simons S, Tameliene R, van Overmeire B, Berger A, Dobrzanska A, Schroth M, Bergqvist L, Courtois E, Rousseau J, Carbajal R; EUROPAIN Survey Working Group of the NeoOpioid Consortium. Assessment of continuous pain in newborns admitted to NICUs in 18 European countries. Acta Paediatrica 2017; 106(8): 1248−1259. doi: 10.1111/apa.13810. doi: 10.1111/apa.13810. https://pubmed.ncbi.nlm.nih.gov/28257153/