Secreted vesicles of the human intestinal microbiota in health and disease

The research group is interested in enlightening the role and functional significance of intestinal microbiota in health and human diseases such as inflammatory bowel disease and intestinal cancer.

Project information

Project duration

-

Funded by

Multiple sources (Spearhead projects of centres for multidisciplinary research)

Project coordinator

University of Oulu

Contact information

Contact person

Project description

Strategic research project of the University of Oulu

Focus institute: Biocenter Oulu

Faculty: Faculty of Medicine (FMED)

The research group is interested in enlightening the role and functional significance of intestinal microbiota in health and human diseases such as inflammatory bowel disease and intestinal cancer. In addition to understanding the role of microbiota in these pathologies, the group aims to identify completely novel antimicrobial molecules with potential medicinal purposes by studying multi-resistant enteric bacteria (e.g. ESBL- and CPE-strains) and their relation to other members of the gastrointestinal microbiome. The research methodologies applied include basic molecular biology tools, host-microbe and microbe-microbe interactomics, a novel state-of-the-art metagenomic phage display technique, next generation sequencing, bioinformatics, and metagenomics.