Daniela Ungureanu
Docent
Associate Prof. (tenure track, Profi6 Fibrobesity)
Molecular biology; Cancer; Pseudokinases; Fibrobesity;
Disease Networks
Faculty of Biochemistry and Molecular Medicine
My research focuses on understanding the signaling networks controlled by receptor tyrosine kinases (RTKs) during normal and aberrant cell growth such cancer. My goal is to assess the signaling pathways employed by Wnt-ligands binding RTKs in cancers and implement our research tools to determine to what extent targeting these molecules (alone or in combination) will improve cancer therapy.
We are working with patient-derived tumor cells and perform molecular profiling such as assessments of cell growth in 2D and 3D, ex-vivo high throughput drug-responses analysis and transcriptomic profiling at the single cell level. This detailed information will help us to understand why/how these cancer cells respond differently to the various treatments, which could significantly improve cancer therapy in the future.
Research interests
- ovarian cancer;
- drug testing;
- scRNA-seq;
- DSRT
- patient-derived ex-vivo models;
- pseudokinases
- Wnt signaling
Researcher information
Research groups
Researcher profiles
Contact information
Visiting address
Internal mail: 5BMTK
Office: 483B
Postal address
University of Oulu
PL 5400 / PO Box 5400
90014 Oulun yliopisto
Finland
