Thesis 14.06.2024 Role of fatty acyl-CoA synthetase FadD5 and ATPase Mkl in Mycobacterium tuberculosis lipid metabolism and transport
Thesis 24.05.2024 Hypoxia response in neurological diseases. The role of HIF-P4H inhibition in Alzheimer’s disease and PHYH deficiency in Refsum disease
Thesis 26.04.2024 The roles of collagen synthesis enzymes in tumorigenesis and metastasis, with focus on tumor stroma and pancreatic cancer as a model
Thesis 15.12.2023 Biochemical and structural studies of E3 ubiquitin ligase DTX3L – a protein at a crossroads of ubiquitination and ADP-ribosylation
Thesis 14.12.2023 Structures and molecular functions of myelin proteins associated with leukodystrophy and peripheral neuropathies
Thesis 08.12.2023 Regulatory Mechanisms of T cell differentiation in inflammation: Modulation of Th subset differentiation in low oxygen condition.
Thesis 19.09.2023 Investigation of the role of extracellular vesicles in induction of nephrogenesis using a flexible model of nephrogenesis
Thesis 15.08.2023 Structure and function of actin depolymerizing factors of the malaria parasite and its vector
Thesis 27.06.2023 The deubiquitinase USP28 and its role in blood cell differentiation and cytokine signaling
Thesis 26.05.2023 Targeting mechanisms of kidney ontogenesis: Roles of endothelial progenitors and Wnt5a signaling
Thesis 23.05.2023 Disease-associated roles of two 2-oxoglutarate dependent dioxygenases, transmembrane prolyl 4-hydroxylase and lysyl hydroxylase 3
Thesis 28.04.2023 Structural and functional characterisation of hereditary polyneuropathy-associated protein N-myc downstream regulated gene 1 (NDRG1)
Thesis 03.03.2023 Prolyl 4-hydroxylases as therapeutic targets. HIF and collagen prolyl 4-hydroxylases in hypertrophic cardiac disease and pulmonary fibrosis, respectively.
Thesis 17.02.2023 Deciphering functional effects of genetic variants on cancer predisposition and progression using an informatics approach
Thesis 27.01.2023 Characterization of the role of HIF prolyl 4-hydroxylases in metabolism and adipocyte differentiation and transmembrane prolyl 4-hydroxylase in aged tissues