Studies on the physiological roles of carbonyl reductase 4 (CBR4) in mitochondrial function
Thesis event information
Date and time of the thesis defence
Place of the thesis defence
K101 Lecture Hall of the Faculty of Biochemistry and Molecular Medicine (Aapistie 7A)
Topic of the dissertation
Studies on the physiological roles of carbonyl reductase 4 (CBR4) in mitochondrial function
Doctoral candidate
Master of Science Ali Julfiker Md Masud
Faculty and unit
University of Oulu Graduate School, Faculty of Biochemistry and Molecular Medicine, Disease network
Subject of study
Biochemistry and Molecular Medicine
Opponent
Docent Jukka Kallijärvi, University of Helsinki
Custos
University Researcher Alexander Kastaniotis, University of Oulu
Studies on the physiological roles of carbonyl reductase 4 (CBR4) in mitochondrial function
The mitochondrial fatty acid synthesis (mtFAS) pathway is a newly discovered metabolic process in mitochondria. Aberrant functioning of this metabolic pathway can lead to neurogenerative diseases. This, together with results from animal experiments, indicates that the mtFAS pathway is essential in mammals. The study introduces a novel aspect of CBR4 function, operating at the interface of mitochondrial lipid metabolism and control of mitochondrial biogenesis and function.
Last updated: 21.11.2024