Breast Cancer Genetics Research Group
Research group information
Unit and faculty
Contact information
Research group leader
- Professor
Researchers
Research group description
The focus of our Breast Cancer Genetics team is on resolving the molecular genetics and biology behind the inherited breast cancer predisposition. For this we use breast cancer case cohorts collected from Northern Finnish population with homogenous genetic background and implement several high-throughput genomic methods for their comprehensive genetic analysis. The effects of the breast cancer predisposing variants are investigated with functional genomics, biochemical and tumor modelling approaches, which can provide important insights into the tumorigenesis mechanisms and may lead to implementation of more effective diagnostic and prognostic tools, as well as targeted treatment.
We anticipate that this project combining the expertise in molecular and clinical genetics, biochemical investigations, and tumor modelling together with the dedicated collaborators will refine the clinical risk assessment of high-risk individuals, increase the understanding of the cellular mechanisms behind breast cancer development and ultimately promote the development of more targeted cancer therapies.
Research Unit of Translational Medicine, Medical Faculty
Contact: katri.pylkas@oulu.fi; katri.pylkas@nordlab.fi